t-Plasminogen activator EC#: 3.4.21.68; ChemWhat Code: 1380580
| Product Name | t-Plasminogen activator |
| Example Structure |  |
| Synonyms | Alteplase, BAT-PA, desmoteplase, DSPA beta, DSPA gamma, EC 3.4.21.31, EC 3.4.99.26, human tissue-type plasminogen activator, IV t-PA, IV tissue plasminogen activator, More, plasminogen activator, Plasminogen activator, tissue-type, r-tPA, recombinant tissue plasminogen activator, Reteplase, rt-PA, rtPA, sc-tPA, sctPA, single chain enzyme tPA, t-PA, t-PA protein, t-plasminogen activator, tc-tPA, tctPA, Tissue plasminogen activator, tissue type plasminogen activator, tissue-plasminogen activator, Tissue-type plasminogen activator, tissue-type plasmiongen activator, tPA, two chain tPA |
| EC Number | 3.4.21.68 |
| CAS Registry Number | 139639-23-9 |
| Comments | A peptidase of family?S1?(trypsin family) from a wide variety of mammalian tissues, especially endothelial cells. Secreted as a single chain precursor which is cleaved to a two-chain form by plasmin. Activity is considerably enhanced by fibrin. Formerly included in EC?3.4.21.31?and EC?3.4.99.26. |
| Cofactor | |
| History | |
| Reactions | Specific cleavage of Arg-|-Val bond in plasminogen to form plasmin. |
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