Axitinib • ChemWhat | Database of Chemicals & Biologicals

Axitinib Nitroso Impurity 3 CAS#: N/A

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Axitinib Nitroso Impurity 3 is chemically N-Methyl-2-((1-nitroso-1H-indazol-6-yl)thio)benzamide. Axitinib Nitroso Impurity 3 is supplied with detailed characterization data compliant with regulatory guideline. Axitinib Nitroso Impurity 3 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Axitinib . The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Axitinib Nitroso Impurity 4 CAS#: N/A

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Axitinib Nitroso Impurity 4 is chemically 2-((3-Iodo-1-nitroso-1H-indazol-6-yl)thio)-N-methylbenzamide. Axitinib Nitroso Impurity 4 is supplied with detailed characterization data compliant with regulatory guideline. Axitinib Nitroso Impurity 4 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Axitinib . The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Axitinib Impurity 16 CAS#: 886230-75-7

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Axitinib Impurity 16 is chemically (E)-6-Nitro-3-(2-(pyridin-2-yl)vinyl)-1-(tetrahydro-2H-pyran-2-yl)-1H-indazole. Axitinib Impurity 16 is supplied with detailed characterization data compliant with regulatory guideline. Axitinib Impurity 16 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Axitinib . The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Axitinib Impurity 25 CAS#: 147-93-3

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Axitinib Impurity 25 is chemically 2-Mercaptobenzoic acid. Axitinib Impurity 25 is supplied with detailed characterization data compliant with regulatory guideline. Axitinib Impurity 25 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Axitinib . The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Axitinib Nitroso Impurity 2 CAS#: N/A

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Axitinib Nitroso Impurity 2 is chemically 6-Iodo-1-nitroso-1H-indazole. Axitinib Nitroso Impurity 2 is supplied with detailed characterization data compliant with regulatory guideline. Axitinib Nitroso Impurity 2 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Axitinib . The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Axitinib Impurity 26 CAS#: 885126-34-1

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Axitinib Impurity 26 is chemically 2-((3-Iodo-1H-indazol-6-yl)thio)-N-methylbenzamide. Axitinib Impurity 26 is supplied with detailed characterization data compliant with regulatory guideline. Axitinib Impurity 26 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Axitinib . The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Axitinib-d3 CAS#: 1126623-89-9

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Axitinib-d3 is chemically (E)-N-(Methyl-d3)-2-((3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)benzamide. Axitinib-d3 is supplied with detailed characterization data compliant with regulatory guideline. Axitinib-d3 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Axitinib . The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Axitinib Impurity 24 CAS#: 1862-88-0

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Axitinib Impurity 24 is chemically 2-Hydroxy-N-methylbenzamide. Axitinib Impurity 24 is supplied with detailed characterization data compliant with regulatory guideline. Axitinib Impurity 24 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Axitinib . The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

N-Nitroso Axitinib CAS#: N/A

By great_watson-int, 6th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

N-Nitroso Axitinib is chemically (E)-N-methyl-2-((1-nitroso-3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)benzamide. N-Nitroso Axitinib is supplied with detailed characterization data compliant with regulatory guideline. N-Nitroso Axitinib can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Axitinib . The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Axitinib Impurity 17 CAS#: N/A

By great_watson-int, 6th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Axitinib Impurity 17 is chemically (E)-6-((2-(methylcarbamoyl)phenyl)sulfonyl)-3-(2-(1-oxidopyridin-2-yl)vinyl)-1H-indazole 1-oxide . Axitinib Impurity 17 is supplied with detailed characterization data compliant with regulatory guideline. Axitinib Impurity 17 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Axitinib . The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Product Name	Axitinib Nitroso Impurity 3
Molecular Structure
CAS Registry Number	N/A
EINECS Number
MDL Number
Beilstein Registry Number
Synonyms	N-Methyl-2-((1-nitroso-1H-indazol-6-yl)thio)benzamide
Molecular Formula	C15H12N4O2S
Molecular Weight	312.3
InChI
InChI Key
Canonical SMILES	O=C(NC)C1=CC=CC=C1SC2=CC3=C(C=C2)C=NN3N=O

Product Name	Axitinib Nitroso Impurity 4
Molecular Structure
CAS Registry Number	N/A
EINECS Number
MDL Number
Beilstein Registry Number
Synonyms	2-((3-Iodo-1-nitroso-1H-indazol-6-yl)thio)-N-methylbenzamide
Molecular Formula	C15H11IN4O2S
Molecular Weight	438.2
InChI
InChI Key
Canonical SMILES	O=C(NC)C1=CC=CC=C1SC2=CC3=C(C=C2)C(I)=NN3N=O

Product Name	Axitinib Impurity 16
Molecular Structure
CAS Registry Number	886230-75-7
EINECS Number
MDL Number
Beilstein Registry Number
Synonyms	(E)-6-Nitro-3-(2-(pyridin-2-yl)vinyl)-1-(tetrahydro-2H-pyran-2-yl)-1H-indazole
Molecular Formula	C19H18N4O3
Molecular Weight	350.4
InChI
InChI Key
Canonical SMILES	O=[N+](C1=CC2=C(C=C1)C(/C=C/C3=NC=CC=C3)=NN2C4CCCCO4)[O-]

Product Name	Axitinib Impurity 25
Molecular Structure
CAS Registry Number	147-93-3
EINECS Number
MDL Number
Beilstein Registry Number
Synonyms	2-Mercaptobenzoic acid
Molecular Formula	C7H6O2S
Molecular Weight	154.2
InChI
InChI Key
Canonical SMILES	OC(C(C=CC=C1)=C1S)=O

Product Name	Axitinib Nitroso Impurity 2
Molecular Structure
CAS Registry Number	N/A
EINECS Number
MDL Number
Beilstein Registry Number
Synonyms	6-Iodo-1-nitroso-1H-indazole
Molecular Formula	C7H4IN3O
Molecular Weight	273.0
InChI
InChI Key
Canonical SMILES	O=NN1N=CC2=C1C=C(I)C=C2

Product Name	Axitinib Impurity 26
Molecular Structure
CAS Registry Number	885126-34-1
EINECS Number
MDL Number
Beilstein Registry Number
Synonyms	2-((3-Iodo-1H-indazol-6-yl)thio)-N-methylbenzamide
Molecular Formula	C15H12IN3OS
Molecular Weight	409.2
InChI
InChI Key
Canonical SMILES	IC1=NNC2=CC(SC(C=CC=C3)=C3C(NC)=O)=CC=C21

Product Name	Axitinib-d3
Molecular Structure
CAS Registry Number	1126623-89-9
EINECS Number
MDL Number
Beilstein Registry Number
Synonyms	(E)-N-(Methyl-d3)-2-((3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)benzamide
Molecular Formula	C22H15D3N4OS
Molecular Weight	389.5
InChI
InChI Key
Canonical SMILES	O=C(NC([2H])([2H])[2H])C1=C(C=CC=C1)SC2=CC=C3C(/C=C/C4=CC=CC=N4)=NNC3=C2

Product Name	Axitinib Impurity 24
Molecular Structure
CAS Registry Number	1862-88-0
EINECS Number
MDL Number
Beilstein Registry Number
Synonyms	2-Hydroxy-N-methylbenzamide
Molecular Formula	C8H9NO2
Molecular Weight	151.2
InChI
InChI Key
Canonical SMILES	O=C(C(C=CC=C1)=C1O)NC

Product Name	N-Nitroso Axitinib
Molecular Structure
CAS Registry Number	N/A
EINECS Number
MDL Number
Beilstein Registry Number
Synonyms	(E)-N-methyl-2-((1-nitroso-3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)benzamide
Molecular Formula	C22H17N5O2S
Molecular Weight	415.5
InChI
InChI Key
Canonical SMILES	O=C(NC)C1=C(C=CC=C1)SC2=CC=C3C(/C=C/C4=CC=CC=N4)=NN(N=O)C3=C2

Product Name	Axitinib Impurity 17
Molecular Structure
CAS Registry Number	N/A
EINECS Number
MDL Number
Beilstein Registry Number
Synonyms	(E)-6-((2-(methylcarbamoyl)phenyl)sulfonyl)-3-(2-(1-oxidopyridin-2-yl)vinyl)-1H-indazole 1-oxide
Molecular Formula	C22H18N4O5S
Molecular Weight	450.5
InChI
InChI Key
Canonical SMILES	[O-][N+]1=CC=CC=C1/C=C/C2=N[NH+]([O-])C3=C2C=CC(S(=O)(C4=CC=CC=C4C(NC)=O)=O)=C3