| Product Name |
taxadien-5alpha-ol O-acetyltransferase |
| Example Structure |
 |
| Synonyms |
acetyl coenzyme A:taxa-4(20),11(12)-dien-5alpha-ol O-acetyl transferase, TAX1 acetyltransferase, TAX19 acetyltransferase, taxadienol acetyl transferase, taxoid-O-acetyltransferase, TmTAT |
| EC Number |
2.3.1.162 |
| CAS Registry Number |
229032-29-5 |
| Comments |
This is the third enzyme in the biosynthesis of the diterpenoid antineoplastic drug taxol (paclitaxel), which is widely used in the treatment of carcinomas, sarcomas and melanomas. |
| Cofactor |
|
| History |
|
| Reactions |
Acetyl-CoA + taxa-4(20),11-dien-5-alpha-ol = CoA + taxa-4(20),11-dien-5- alpha-yl acetate. |
