taxane 10beta-hydroxylase EC#: 1.14.14.105; ChemWhat Code: 1375613
Product Name | taxane 10beta-hydroxylase |
Example Structure | |
Synonyms | 5-alpha-taxadienol-10-beta-hydroxylase, cytochrome P450 reductase, NADPH:cytochrome P450 reductase, oxygenase, taxane 10beta-mono-, taxa-4(20),11-dien-5alpha-yl acetate 10beta-hydroxylase, taxadien-5alpha-yl-acetate 10beta-hydroxylase, taxane 10beta-hydroxylase, taxane 10beta-monooxygenase, taxoid 10beta-hydroxylase, THY10b, Tm10BH |
EC Number | 1.14.14.105 |
CAS Registry Number | 337514-75-7 |
Comments | This microsomal cytochrome-P450 (heme-thiolate) enzyme from the plant Taxus cuspidata is involved in the biosynthesis of the diterpenoid antineoplastic drug taxol (paclitaxel). Formerly EC 1.14.13.76. |
Cofactor | heme-thiolate |
History | |
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