tetrachlorohydroquinone reductive dehalogenase EC#: 1.21.4.5; ChemWhat Code: 1376092
| Product Name | tetrachlorohydroquinone reductive dehalogenase |
| Example Structure |  |
| Synonyms | PCP hydroxylase, pcpC, TCHQ dehalogenase, tetrachloro-p-hydroquinone reductive dehalogenase, tetrachlorohydroquinone dehalogenase, tetrachlorohydroquinone reductive dehalogenase |
| EC Number | 1.21.4.5 |
| CAS Registry Number | |
| Comments | The enzyme, characterized from the bacterium Sphingobium chlorophenolicum, converts tetrachlorohydroquinone to 2,6-dichlorohydroquinone in two steps, via 2,3,6-trichlorohydroquinone, using glutathione as the reducing agent. The enzyme is sensitive to oxidation – when an internal L-cysteine residue is oxidized, the enzyme produces 2,3,5-trichloro-6-(glutathion-S-yl)-hydroquinone and 2,6-dichloro-3-(glutathion-S-yl)-hydroquinone instead of its normal products. |
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