Thermitase EC#: 3.4.21.66; ChemWhat Code: 1380577

Product Name Thermitase
Example Structure Example Structure of Thermitase EC#: 3.4.21.66
Synonyms EC 3.4.21.14, PLLA-degrading enzyme, PrlA, Proteinase, Thermoactinomyces vulgaris serine, proteolysin, Thermoactinomyces vulgaris serine proteinase, Thermophilic Streptomyces serine proteinase, thermostable serine protease
EC Number 3.4.21.66
CAS Registry Number 69772-87-8
Comments A peptidase of family?S8?(subtilisin family) from?Thermoactinomyces vulgaris?containing a single Cys, near the active site His, and inhibited by?p-mercuribenzoate. The N-terminal extension of the polypeptide chain relative to subtilisin contributes to Ca2+-binding and the high thermostability. The amino acid composition and properties of the thermostable enzyme from?Streptomyces rectus?var.?proteolyticus?(formerly included in EC?3.4.21.14) are closely similar [1,2].
Cofactor
History
Reactions Hydrolysis of proteins, including collagen.

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