thermolysin EC#: 3.4.24.27; ChemWhat Code: 1380996
| Product Name | thermolysin |
| Example Structure |  |
| Synonyms | Bacillus thermoproteolyticus neutral proteinase, EC 3.4.24.4, hspA, Neutral metalloproteinase, NprM, protease type X, proteinase type X, Proteinase, Bacillus thermoproteolyticus neutral, protex 14L, Thermoase, thermoase PC10F, Thermoase Y10, thermolysin, thermolysin-like protease, Thermostable neutral proteinase, TL, TLN, TLP, TLP-ste |
| EC Number | 3.4.24.27 |
| CAS Registry Number | 9073-78-3 |
| Comments | A thermostable extracellular metalloendopeptidase containing four calcium ions. Enzymes that may be species variants of thermolysin are reported from?Micrococcus caseolyticus?[4] and?Aspergillus oryzae?[5]. Formerly included in EC?3.4.24.4. Type example of peptidase family?M4. Closely related but distinct enzymes are aeromonolysin, pseudolysin, bacillolysin, aureolysin and mycolysin. |
| Cofactor | Zn2+;Ca2+ |
| History | |
| Reactions | Preferential cleavage: Xaa-|-Leu > Xaa-|-Phe. |
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