thiosulfate dehydrogenase EC#: 1.8.2.2; ChemWhat Code: 1374697

Product Name thiosulfate dehydrogenase
Example Structure Example Structure of thiosulfate dehydrogenase EC#: 1.8.2.2
Synonyms AFE_0042, Alvin_0091, AvTsdA, C8J_0815, diheme cytochrome c TsdA, enzymes, thiosulfate-oxidizing, MpTsdBA, oxidase, thiosulfate, Tat pathway signal sequence domain protein, tetrathionate synthase, thiosulfate dehydrogenase, thiosulfate oxidase, thiosulfate-acceptor oxidoreductase, thiosulfate-oxidizing enzyme, TsdA
EC Number 1.8.2.2
CAS Registry Number 9076-88-4
Comments The enzyme catalyses the reversible formation of a sulfur-sulfur bond between the sulfane atoms of two thiosulfate molecules, yielding tetrathionate and releasing two electrons. In many bacterial species the enzyme is a diheme c-type cytochrome. In a number of organisms, including Thiomonas intermedia and Sideroxydans lithotrophicus, a second diheme cytochrome (TsdB) acts as the electron acceptor. However, some organisms, such as Allochromatium vinosum, lack TsdB. The electron acceptor in these organisms may be the high-potential iron-sulfur protein (HiPIP).
Cofactor
History
Reactions 2 thiosulfate + 2 ferricytochrome c = tetrathionate + 2 ferrocytochrome c.

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