thymine dioxygenase EC#: 1.14.11.6; ChemWhat Code: 1375077
| Product Name | thymine dioxygenase |
| Example Structure | ![]() |
| Synonyms | 5-hydroxy-methyluracil dioxygenase, 5-hydroxy-methyluracil oxygenase, Fe2+/2-oxoglutarate dependent hydroxylase, J binding protein 1, J binding protein 2, J-binding protein 1, J-binding protein 2, JBP1, JBP2, More, T7H, thymidine hydroxylase, thymine 7-hydroxylase, thymine dioxygenase, thymine hydroxylase, thymine-7-hydroxylase |
| EC Number | 1.14.11.6 |
| CAS Registry Number | 37256-67-0 |
| Comments | Requires Fe2+ and ascorbate. Also acts on 5-hydroxymethyluracil to oxidize its -CH2OH group first to -CHO and then to -COOH. |
| Cofactor | Fe2+;L-ascorbate |
| History | |
| Reactions | Thymine + 2-oxoglutarate + O(2) = 5-hydroxymethyluracil + succinate + CO(2). |
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