thyroid-hormone transaminase EC#: 2.6.1.26; ChemWhat Code: 1378159

Product Name thyroid-hormone transaminase
Example Structure Example Structure of thyroid-hormone transaminase EC#: 2.6.1.26
Synonyms 3,5-dinitrotyrosine transaminase, aminotransferase, thyroid hormone
EC Number 2.6.1.26
CAS Registry Number 51004-29-6
Comments A pyridoxal-phosphate protein. Acts on monoiodotyrosine, diiodotyrosine, triiodothyronine, thyroxine and dinitrotyrosine (unlike EC?2.6.1.24?diiodotyrosine transaminase, which does not act on dinitrotyrosine). Pyruvate or oxaloacetate can act as acceptors.
Cofactor pyridoxal 5′-phosphate
History
Reactions L-3,5,3′-triiodothyronine + 2-oxoglutarate = 3-(4-(4-hydroxy-3- iodophenoxy)-3,5-diiodophenyl)-2-oxopropanoate + L-glutamate.

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