trans-4-coumaroyl-CoA 2-hydroxylase EC#: 1.14.11.62; ChemWhat Code: 1375158
| Product Name | trans-4-coumaroyl-CoA 2-hydroxylase |
| Example Structure |  |
| Synonyms | C2’H, CYP98A22, Diox4 |
| EC Number | 1.14.11.62 |
| CAS Registry Number | |
| Comments | Requires iron(II) and ascorbate. The product spontaneously undergoes trans-cis isomerization followed by lactonization and cyclization, liberating CoA and forming umbelliferone. The enzymes from the plants Ruta graveolens and Ipomoea batatas also act on trans-feruloyl-CoA (cf. EC 1.14.11.61, feruloyl-CoA 6′-hydroxylase). |
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