trimethylamine monooxygenase EC#: 1.14.13.148; ChemWhat Code: 1375380

Product Name trimethylamine monooxygenase
Example Structure Example Structure of trimethylamine monooxygenase EC#: 1.14.13.148
Synonyms EC 1.14.13.8, FAD-containing monooxygenase, flavin containing monooxygenase 3, flavin monooxygenase 3, flavin-containing monooxygenase, flavin-containing monooxygenase 3, FMO, FMO3, FMO4, TMA monooxygenase, TMA N-oxygenase, TMM
EC Number 1.14.13.148
CAS Registry Number
Comments A flavoprotein. The bacterial enzyme enables bacteria to use trimethylamine as the sole source of carbon and energy [1,4]. The mammalian enzyme is involved in detoxification of trimethylamine. Mutations in the human enzyme cause the inheritable disease known as trimethylaminuria (fish odor syndrome) [2,3].
Cofactor flavoprotein
History
Reactions N,n,N-trimethylamine + nadph + O(2) = n,n,N-trimethylamine N-oxide + NADP(+) + H(2)O.

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