| Product Name |
trimethylamine monooxygenase |
| Example Structure |
 |
| Synonyms |
EC 1.14.13.8, FAD-containing monooxygenase, flavin containing monooxygenase 3, flavin monooxygenase 3, flavin-containing monooxygenase, flavin-containing monooxygenase 3, FMO, FMO3, FMO4, TMA monooxygenase, TMA N-oxygenase, TMM |
| EC Number |
1.14.13.148 |
| CAS Registry Number |
|
| Comments |
A flavoprotein. The bacterial enzyme enables bacteria to use trimethylamine as the sole source of carbon and energy [1,4]. The mammalian enzyme is involved in detoxification of trimethylamine. Mutations in the human enzyme cause the inheritable disease known as trimethylaminuria (fish odor syndrome) [2,3]. |
| Cofactor |
flavoprotein |
| History |
|
| Reactions |
N,n,N-trimethylamine + nadph + O(2) = n,n,N-trimethylamine N-oxide + NADP(+) + H(2)O. |
