| Product Name |
tRNA-5-methyluridine54 2-sulfurtransferase |
| Example Structure |
 |
| Synonyms |
PH0300, TTC0106, TtuA, TT_C0106, Veg136 protein |
| EC Number |
2.8.1.15 |
| CAS Registry Number |
|
| Comments |
The enzyme, found in thermophilic bacteria such as?Thermus thermophilus?and archaea such as?Pyrococcus horikoshii, modifies the ribothymidine (5-methyluridine) residue at position 54 of tRNAs. Contains zinc. |
| Cofactor |
Zn2+ |
| History |
|
| Reactions |
Atp + [TtuB sulfur-carrier protein]-Gly-NH-CH(2)-C(O)SH + 5-methyluracil(54) in tRNA + H(2)O = Amp + diphosphate + 5-methyl-2- thiouracil(54) in tRNA + [TtuB sulfur-carrier protein]-Gly-Gly. |
