tRNA-guanine15 transglycosylase EC#: 2.4.2.48; ChemWhat Code: 1377808

Product Name tRNA-guanine15 transglycosylase
Example Structure Example Structure of tRNA-guanine15 transglycosylase EC#: 2.4.2.48
Synonyms archaeosine tRNA-guanine transglycosylase, archaeosine tRNAguanine transglycosylase, ArcTGT, multisite-specific archaeosine tRNA-guanine transglycosylase, Ta1493, TGT, transfer ribonucleic acid guanine15 transglycosylase, tRNA guanine15 transglycosidase, tRNA-guanine transglycosylase
EC Number 2.4.2.48
CAS Registry Number
Comments Archaeal tRNAs contain the modified nucleoside archaeosine at position 15. This archaeal enzyme catalyses the exchange of guanine at position 15 of tRNA with the base preQ0, which is ultimately modified to form the nucleoside archaeosine (cf. EC 2.6.1.97) [1].
Cofactor
History
Reactions Guanine(15) in tRNA + 7-cyano-7-carbaguanine = 7-cyano-7-carbaguanine(15) in tRNA + guanine.

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