tRNA (guanine26-N2)-dimethyltransferase EC#: 2.1.1.216; ChemWhat Code: 1376454
| Product Name | tRNA (guanine26-N2)-dimethyltransferase |
| Example Structure |  |
| Synonyms | Ta0997, Trm1, Trm1 methyltransferase, Trm1p, tRNA (guanine(26)-N(2))-dimethyltransferase, tRNA (m22G26)dimethyltransferase, tRNA(guanine-26,N2-N2) methyltransferase, tRNA(guanine26,N2,N2)-dimethyltransferase, tRNA(m22G26)dimethyltransferase, ZC376.5 |
| EC Number | 2.1.1.216 |
| CAS Registry Number | |
| Comments | The enzyme dissociates from its tRNA substrate between the two consecutive methylation reactions. In contrast to EC 2.1.1.215, tRNA (guanine26-N2/guanine27-N2)-dimethyltransferase, this enzyme does not catalyse the methylation of guanine27 in tRNA. |
| Cofactor | |
| History | |
| Reactions | 2 S-adenosyl-L-methionine + guanine(26) in tRNA = 2 S-adenosyl-L- homocysteine + N(2)-dimethylguanine(26) in tRNA. |
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