Product Name |
tRNAIle2-agmatinylcytidine synthase |
Example Structure |
 |
Synonyms |
AF2259, TiaS, tRNAIle-2-agmatinylcytidine synthetase, tRNAIle-agm2C synthetase, tRNAIle-agmatidine synthetase |
EC Number |
6.3.4.22 |
CAS Registry Number |
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Comments |
The enzyme from the archaeon?Archaeoglobus fulgidus?modifies the wobble base of the CAU anticodon of the archaeal tRNAIle2?at the oxo group in position 2 of cytidine34. This modification is crucial for accurate decoding of the genetic code. In bacteria EC?6.3.4.19, tRNAIle-lysidine synthase, catalyses the modification of [tRNAIle2]-cytidine34?to [tRNAIle2]-lysidine34. |
Cofactor |
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History |
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Reactions |
Atp + agmatine + (tRNA(Ile)(2))-cytidine(34) + H(2)O = (tRNA(Ile)(2))-2- agmatinylcytidine(34) + Amp + 2 phosphate. |