| Product Name |
tRNA:m4X modification enzyme |
| Example Structure |
 |
| Synonyms |
TRM13, Trm13p, tRNA:Xm4 modification enzyme |
| EC Number |
2.1.1.225 |
| CAS Registry Number |
|
| Comments |
The enzyme from Saccharomyces cerevisiae 2′-O-methylates cytidine4 in tRNAPro and tRNAGly(GCC), and adenosine4 in tRNAHis. |
| Cofactor |
|
| History |
|
| Reactions |
(1) S-adenosyl-L-methionine + cytidine(4) in tRNA(Pro) = S-adenosyl-L- homocysteine + 2′-O-methylcytidine(4) in tRNA(Pro). (2) S-adenosyl-L-methionine + cytidine(4) in tRNA(Gly)(GCC) = S-adenosyl- L-homocysteine + 2′-O-methylcytidine(4) in tRNA(Gly)(GCC). (3) S-adenosyl-L-methionine + adenosine(4) in tRNA(His) = S-adenosyl-L- homocysteine + 2′-O-methyladenosine(4) in tRNA(His). |
