tropine acyltransferase EC#: 2.3.1.185; ChemWhat Code: 1376993
| Product Name | tropine acyltransferase |
| Example Structure |  |
| Synonyms | acetyI-CoA:tropine acyltransferase, acetyl-CoA:tropine transferase, tropine:acyl-CoA transferase |
| EC Number | 2.3.1.185 |
| CAS Registry Number | 138440-79-6;162535-29-7 |
| Comments | This enzyme exhibits absolute specificity for the endo/3¦Á configuration found in tropine as pseudotropine (tropan-3¦Â-ol; see EC 2.3.1.186, pseudotropine acyltransferase) is not a substrate [3]. Acts on a wide range of aliphatic acyl-CoA derivatives, with tigloyl-CoA and acetyl-CoA being the best substrates. It is probably involved in the formation of the tropane alkaloid littorine, which is a precursor of hyoscyamine [4]. |
| Cofactor | |
| History | |
| Reactions | An acyl-CoA + tropine = CoA + an O-acyltropine. |
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