tryptophan 2′-dioxygenase EC#: 1.13.99.3; ChemWhat Code: 1375066
| Product Name | tryptophan 2′-dioxygenase |
| Example Structure |  |
| Synonyms | indole-3-alkane alpha-hydroxylase, indolyl-3-alkane alpha-hydroxylase, oxidase, tryptophan side-chain alpha,beta-, oxidase, tryptophan side-chain alpha,beta-, II, tryptophan side chain oxidase, tryptophan side chain oxidase II, tryptophan side chain oxidase type I, tryptophan side-chain alpha,beta-oxidase, tryptophan side-chain oxidase, TSO, TSO I, TSO II |
| EC Number | 1.13.99.3 |
| CAS Registry Number | 64295-81-4;90371-50-9 |
| Comments | A hemoprotein. Acts on a number of indole-3-alkane derivatives, oxidizing the 3-side-chain in the 2′-position. Best substrates were L-tryptophan and 5-hydroxy-L-tryptophan. |
| Cofactor | heme |
| History | |
| Reactions | L-tryptophan + O(2) = (indol-3-yl)glycolaldehyde + CO(2) + NH(3). |
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