tryptophan 6-halogenase EC#: 1.14.19.59; ChemWhat Code: 1375824
| Product Name | tryptophan 6-halogenase |
| Example Structure |  |
| Synonyms | sttH, Thal, ThdH |
| EC Number | 1.14.19.59 |
| CAS Registry Number | |
| Comments | The enzyme is a flavin-dependent halogenase that has been described from several bacterial species. It utilizes molecular oxygen to oxidize the FADH2 cofactor, giving C4a-hydroperoxyflavin, which then reacts with chloride to produce a hypochlorite ion. The latter reacts with an active site lysine to generate a chloramine, which chlorinates the substrate. cf. EC 1.14.19.58, tryptophan 5-halogenase, and EC 1.14.19.9, tryptophan 7-halogenase. |
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