tryptophan N-monooxygenase EC#: 1.14.14.156; ChemWhat Code: 1375664
| Product Name | tryptophan N-monooxygenase |
| Example Structure |  |
| Synonyms | CYP79B1, CYP79B1 monooxygenase, CYP79B2, CYP79B3 |
| EC Number | 1.14.14.156 |
| CAS Registry Number | |
| Comments | A cytochrome P450 (heme-thiolate) protein from the plant Arabidopsis thaliana. This enzyme catalyses two successive N-hydroxylations of L-tryptophan, the first steps in the biosynthesis of both auxin and the indole alkaloid phytoalexin camalexin. The product of the two hydroxylations, N,N-dihydroxy-L-tryptophan, is extremely labile and dehydrates spontaneously. The dehydrated product is then subject to a decarboxylation that produces an oxime. It is still not known whether the decarboxylation is spontaneous or catalysed by the enzyme. Formerly EC 1.14.13.125 and EC 1.14.13.n2. |
| Cofactor | heme-thiolate |
| History | |
| Reactions |
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