type 2 galactoside alpha-(1,2)-fucosyltransferase EC#: 2.4.1.344; ChemWhat Code: 1377685

Product Name type 2 galactoside alpha-(1,2)-fucosyltransferase
Example Structure Example Structure of type 2 galactoside alpha-(1,2)-fucosyltransferase EC#: 2.4.1.344
Synonyms alpha-(1->2)-L-fucosyltransferase, alpha-2-fucosyltransferase, alpha-2-L-fucosyltransferase, beta-galactoside alpha(1->2)fucosyltransferase, blood group H alpha-2-fucosyltransferase, blood-group substance H-dependent fucosyltransferase, FTA, Ftb, FUT1, FUT2, galactoside 2-alpha-L-fucosyltransferase 1, galactoside 2-alpha-L-fucosyltransferase 2, GDP fucose-lactose fucosyltransferase, GDP-beta-L-fucose:beta-D-galactosyl-R 2-alpha-L-fucosyltransferase, GDP-L-fucose:beta-D-galactoside alpha-(1->2)-L-fucosyltransferase, GDP-L-fucose:beta-D-galactoside alpha-2-L-fucosyltransferase, GDP-L-fucose:lactose fucosyltransferase, guanosine diphospho-L-fucose-lactose fucosyltransferase, guanosine diphosphofucose-beta-D-galactosyl-alpha-2-L-fucosyltransferase, guanosine diphosphofucose-galactoside 2-L-fucosyltransferase, guanosine diphosphofucose-galactosylacetylglucosaminylgalactosylglucosylceramide alpha-L-fucosyltransferase, guanosine diphosphofucose-glycoprotein 2-alpha-fucosyltransferase, guanosine diphosphofucose-glycoprotein 2-alpha-L-fucosyltransferase, guanosine diphosphofucose-lactose fucosyltransferase, H-gene-encoded beta-galactoside alpha(1->2)fucosyltransferase
EC Number 2.4.1.344
CAS Registry Number
Comments The enzyme acts on a glycoconjugates where the substituent is a glycoprotein or glycosphingolipid. The recognized moiety of the substrate is known as a type 2 histo-blood group antigen precursor disaccharide, and the action of the enzyme produces an H type 2 antigen. Cf. EC 2.4.1.69.
Cofactor
History
Reactions GDP-beta-L-fucose + beta-D-galactosyl-(1->4)-N-acetyl-beta-D- glucosaminyl-R = Gdp + alpha-L-fucosyl-(1->2)-beta-D-galactosyl-(1->4)-N- acetyl-beta-D-glucosaminyl-R.

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