UDP-2,3-diacetamido-2,3-dideoxyglucuronic acid 2-epimerase EC#: 5.1.3.23; ChemWhat Code: 1383124

Product Name UDP-2,3-diacetamido-2,3-dideoxyglucuronic acid 2-epimerase
Example Structure Example Structure of UDP-2,3-diacetamido-2,3-dideoxyglucuronic acid 2-epimerase EC#: 5.1.3.23
Synonyms 2,3-diacetamido-2,3-dideoxy-alpha-D-glucuronic acid 2-epimerase, UDP-2,3-diacetamido-2,3-dideoxy-alpha-D-glucuronic acid 2-epimerases, UDP-alpha-D-GlcNAc3NAcA 2-epimerase, UDP-GlcNAc3NAcA 2-epimerase, WbpI, WlbD
EC Number 5.1.3.23
CAS Registry Number
Comments This enzyme participates in the biosynthetic pathway for UDP-¦Á-D-ManNAc3NAcA (UDP-2,3-diacetamido-2,3-dideoxy-¦Á-D-mannuronic acid), an important precursor of the B-band lipopolysaccharide of?Pseudomonas aeroginosa?serotype O5 and of the band-A trisaccharide of?Bordetella pertussis, both important respiratory pathogens [1]. The enzyme is highly specific as UDP-¦Á-D-GlcNAc, UDP-¦Á-D-GlcNAcA (UDP-2-acetamido-2-deoxy-¦Á-D-glucuronic acid) and UDP-¦Á-D-GlcNAc3NAc (UDP-2,3-diacetamido-2,3-dideoxy-¦Á-D-glucose) cannot act as substrates [1].
Cofactor
History
Reactions UDP-2,3-diacetamido-2,3-dideoxy-alpha-D-glucuronate = UDP-2,3- diacetamido-2,3-dideoxy-alpha-D-mannuronate.

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