UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-L-glutamate epimerase EC#: 5.1.1.23; ChemWhat Code: 1383066
| Product Name | UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-L-glutamate epimerase |
| Example Structure |  |
| Synonyms | MurL, UDP-MurNAc-L-Ala-L-Glu epimerase, XOO_1319 |
| EC Number | 5.1.1.23 |
| CAS Registry Number | |
| Comments | The enzyme, characterized from the bacterium?Xanthomonas oryzae, catalyses epimerization of the terminal?L-glutamate in UDP-N-acetyl-¦Á-D-muramoyl-L-alanyl-L-glutamate. The reaction proceeds only in one direction and involves an adenylated intermediate. The combined activity of this enzyme and EC?6.3.2.53, UDP-N-acetylmuramoyl-L-alanine¡ªL-glutamate ligase, provides an alternative route for incorporating?D-glutamate into peptidoglycan, replacing the more common combination of EC?5.1.1.3, glutamate racemase, and EC?6.3.2.9, UDP-N-acetylmuramoyl-L-alanine¡ªD-glutamate ligase. |
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