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UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-L-glutamate epimerase EC#: 5.1.1.23; ChemWhat Code: 1383066

Product Name UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-L-glutamate epimerase
Example Structure Example Structure of UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-L-glutamate epimerase EC#: 5.1.1.23
Synonyms MurL, UDP-MurNAc-L-Ala-L-Glu epimerase, XOO_1319
EC Number 5.1.1.23
CAS Registry Number
Comments The enzyme, characterized from the bacterium?Xanthomonas oryzae, catalyses epimerization of the terminal?L-glutamate in UDP-N-acetyl-¦Á-D-muramoyl-L-alanyl-L-glutamate. The reaction proceeds only in one direction and involves an adenylated intermediate. The combined activity of this enzyme and EC?6.3.2.53, UDP-N-acetylmuramoyl-L-alanine¡ªL-glutamate ligase, provides an alternative route for incorporating?D-glutamate into peptidoglycan, replacing the more common combination of EC?5.1.1.3, glutamate racemase, and EC?6.3.2.9, UDP-N-acetylmuramoyl-L-alanine¡ªD-glutamate ligase.
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