UDP-N-acetylglucosamine 4,6-dehydratase (configuration-retaining) EC#: 4.2.1.135; ChemWhat Code: 1382442

Product Name UDP-N-acetylglucosamine 4,6-dehydratase (configuration-retaining)
Example Structure Example Structure of UDP-N-acetylglucosamine 4,6-dehydratase (configuration-retaining) EC#: 4.2.1.135
Synonyms Bc3750, BC_3750, Cj1120c, Pdeg, PglF, UDP-Glc-NAc 4,6-dehydratase, UDP-N-acetylglucosamine C4,6-dehydratase
EC Number 4.2.1.135
CAS Registry Number
Comments Contains NAD+?as a cofactor [2]. This is the first enzyme in the biosynthetic pathway of?N,N’-diacetylbacillosamine [1], the first carbohydrate in the glycoprotein N-linked heptasaccharide in?Campylobacter jejuni. This enzyme belongs to the short-chain dehydrogenase/reductase family of enzymes.
Cofactor NAD+
History
Reactions UDP-N-acetyl-alpha-D-glucosamine = UDP-2-acetamido-2,6-dideoxy-alpha-D- xylo-hex-4-ulose + H(2)O.

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