UDP-N-acetylglucosamine-undecaprenyl-phosphate N-acetylglucosaminephosphotransferase EC#: 2.7.8.33; ChemWhat Code: 1378965
| Product Name | UDP-N-acetylglucosamine-undecaprenyl-phosphate N-acetylglucosaminephosphotransferase |
| Example Structure |  |
| Synonyms | GlcNAc-P-P-Und synthase, GlcNAc:undecaprenyl-phosphate GlcNAc-1-phosphate transferase, GPT, PNPT, polyisoprenyl-phosphate N-acetylaminosugar-1-phosphate transferase, polyprenyl-P N-acetylhexosamine-1-P transferase, Rfe, TagO, UDP-GlcNAc:undecaprenyl phosphate N-acetylglucosaminyl 1-P transferase, UDP-GlcNAc:undecaprenyl-phosphate GlcNAc-1-phosphate transferase, UDP-N-acetylglucosamine:undecaprenyl-phosphate GlcNAc-1-phosphate transferase, undecaprenyl-phosphate N-acetylhexosamine-1-phosphate transferase, undecaprenyl-phosphate-GlcNAc-1-phosphate transferase, WecA, WecA transferase, WecAHP |
| EC Number | 2.7.8.33 |
| CAS Registry Number | |
| Comments | This enzyme catalyses the synthesis of?N-acetyl-¦Á-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol, an essential lipid intermediate for the biosynthesis of various bacterial cell envelope components. The enzyme also initiates the biosynthesis of enterobacterial common antigen and O-antigen lipopolysaccharide in certain?Escherichia coli?strains, including K-12 [2] and of teichoic acid in certain Gram-positive bacteria [4]. |
| Cofactor | |
| History | |
| Reactions | UDP-N-acetyl-alpha-D-glucosamine + ditrans,octacis-undecaprenyl phosphate = Ump + N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis- undecaprenol. |
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