undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase EC#: 2.4.1.227; ChemWhat Code: 1377532
| Product Name | undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase |
| Example Structure |  |
| Synonyms | acetylglucosaminyltransferase, uridine diphosphoacetylglucosamine-acetylmuramoylpentapeptide pyrophospholipid, gene murG enzyme, gene murG proteins, Lipid I acetylglucosaminyltransferase, MurG, MurG glycosyltransferase, MurG transferase, peptidoglycan glycosyltransferase, proteins, gene murG, translocase II, UDP-acetylglucosamine-acetylmuramoylpentapeptide pyrophospholipid acetylglucosaminyltransferase |
| EC Number | 2.4.1.227 |
| CAS Registry Number | 60976-26-3 |
| Comments | The enzyme also works when the lysine residue is replaced by meso-2,6-diaminoheptanedioate (meso-2,6-diaminopimelate, A2pm) combined with adjacent residues through its L-centre, as it is in Gram-negative and some Gram-positive organisms. The undecaprenol involved is ditrans,octacis-undecaprenol. |
| Cofactor | |
| History | |
| Reactions | UDP-N-acetylglucosamine + Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D- Ala)-diphosphoundecaprenol = Udp + GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma- D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol. |
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