uronate dehydrogenase EC#: 1.1.1.203; ChemWhat Code: 1373274
| Product Name | uronate dehydrogenase |
| Example Structure |  |
| Synonyms | Atu3143, CsUDH, galacturonate acid reductase, GalUR, PfUDH, PmUDH, PnUDH, PSPTO_1053, PsUDH, Udh, uronate dehydrogenase, uronate:NAD-oxidoreductase, uronic acid dehydrogenase |
| EC Number | 1.1.1.203 |
| CAS Registry Number | 37250-98-9 |
| Comments | Requires Mg2+. The enzyme, characterized from the bacterium Agrobacterium fabrum, participates in oxidative degradation pathways for galacturonate and glucuronate. The enzyme can only accept the ¦Â anomeric form of the substrate [4]. The 1,5 lactone product is rather stable at cytosolic pH and does not hydrolyse spontaneously at a substantial rate. Formerly EC 1.2.1.35. |
| Cofactor | Mg2+ |
| History | |
| Reactions | (1) Beta-D-galacturonate + NAD(+) = D-galactaro-1,5-lactone + Nadh. (2) Beta-D-glucuronate + NAD(+) = D-glucaro-1,5-lactone + Nadh. |
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