verruculogen synthase EC#: 1.14.11.38; ChemWhat Code: 1375126

Product Name verruculogen synthase
Example Structure Example Structure of verruculogen synthase EC#: 1.14.11.38
Synonyms fmtF, FmtOx1, FtmF
EC Number 1.14.11.38
CAS Registry Number
Comments Requires Fe2+ and ascorbate. Found in the fungus Aspergillus fumigatus. Both atoms of a dioxygen molecule are incorporated into verruculogen [1,2]. Involved in the biosynthetic pathways of several indole alkaloids such as fumitremorgin A.
Cofactor Fe2+
History
Reactions Fumitremorgin B + 2-oxoglutarate + 2 O(2) + AH(2) = verruculogen + succinate + CO(2) + H(2)O + A.

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