very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase EC#: 4.2.1.134; ChemWhat Code: 1382441
| Product Name | very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase |
| Example Structure |  |
| Synonyms | 3 hydroxyacyl-CoA dehydratase, 3-hydroxyacyl-CoA dehydratase, Fatty acid elongase, fatty acyl-CoA dehydratase, HACD1, HACD2, HACD3, HACD4, HCD, PAS2, PASTICCINO 2, PASTICCINO2, PHS1, PTPLA, PTPLA dehydratase, very-long-chain (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase, very-long-chain hydroxy fatty acyl-CoA dehydratase |
| EC Number | 4.2.1.134 |
| CAS Registry Number | |
| Comments | This is the third component of the elongase, a microsomal protein complex responsible for extending palmitoyl-CoA and stearoyl-CoA (and modified forms thereof) to very-long chain acyl CoAs.?cf. EC?2.3.1.199, very-long-chain 3-oxoacyl-CoA synthase, EC?1.1.1.330, very-long-chain 3-oxoacyl-CoA reductase, and EC?1.3.1.93, very-long-chain enoyl-CoA reductase. |
| Cofactor | |
| History | |
| Reactions | A very-long-chain (3R)-3-hydroxyacyl-CoA = a very-long-chain trans-2,3- dehydroacyl-CoA + H(2)O. |
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