XTP/dITP diphosphatase EC#: 3.6.1.66; ChemWhat Code: 1381640

Product Name XTP/dITP diphosphatase
Example Structure Example Structure of XTP/dITP diphosphatase EC#: 3.6.1.66
Synonyms Af2237, dITP/XTP pyrophosphatase, Ec197, hypoxanthine/xanthine dNTP pyrophosphatase, Mj0226, PH1917, TM0159
EC Number 3.6.1.66
CAS Registry Number
Comments The enzymes from the bacterium?Escherichia coli?and the archaea?Methanococcus jannaschii?and?Archaeoglobus fulgidus?are highly specific for XTP, dITP and ITP. The activity is dependent on divalent cations, Mg2+?is preferred.
Cofactor Mg2+
History
Reactions (1) Xtp + H(2)O = xmp + diphosphate. (2) dITP + H(2)O = dIMP + diphosphate. (3) Itp + H(2)O = imp + diphosphate.

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