Recombinant Human Eotaxin-2/CCL24 (rHuEotaxin-2/CCL24, O00175, 6369) CAS#: 204-24-1816; ChemWhat Code: 1404226

Official Full Name Recombinant Human Eotaxin-2/CCL24 (rHuEotaxin-2/CCL24)
Squence Squence of Recombinant Human Eotaxin-2/CCL24
Amino Acid Sequence VVIPSPCCMF FVSKRIPENR VVSYQLSSRS TCLKAGVIFT TKKGQQFCGD PKQEWVQRYM KNLDAKQKKA SPRARAVA
Synonyms CK-beta-6, MPIF-2, Small-inducible Cytokine A24
Accession Number O00175
GeneID 6369
Summary CCL24 is a secreted protein, encoded by CCL24 gene in humans located on Chr.7, and produced by activated monocytes and T lymphocytes. CCL24 has functions of chemotactic activity for resting T-lymphocytes and eosinophils, but none for monocytes and activated lymphocytes. The plasma levels of CCL24 and the aspirin-exacerbated respiratory disease (such as asthma) morbidity rate have positive correlation.
Source Escherichia coli.
Molecular Weight Approximately 8.8 kDa, a single non-glycosylated polypeptide chain containing 78 amino acids.
Biological Activity Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human peripheral blood eosinophils is in a concentration of 50-100 ng/ml.
Appearance Sterile filtered white lyophilized (freeze-dried) powder.
Formulation Lyophilized from a 0.2 um filtered concentrated solution in 20 mM PB, pH 7.4, 150 mM NaCl.
Endotoxin Less than 1 EU/ug of rHuEotaxin-2/CCL24 as determined by LAL method.
Reconstitution We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- 12 months from date of receipt, -20 to -70 °C as supplied.- 1 month, 2 to 8 °C under sterile conditions after reconstitution.- 3 months, -20 to -70 °C under sterile conditions after reconstitution.
References
SDS-PAGE SDS-PAGE of Recombinant Human Eotaxin-2/CCL24
Safety Data Sheet (SDS) Download Click to download
Technical Data Sheet (TDS) Download Click to download

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