L-seryl-tRNASec selenium transferase EC#: 2.9.1.1

Product Name L-seryl-tRNASec selenium transferase
Example Structure Example Structure of L-seryl-tRNASec selenium transferase EC#: 2.9.1.1
Synonyms Cysteinyl-tRNA(Sec) selenium transferase, Cysteinyl-tRNASec-selenium transferase, CysteinyltRNASel-selenium transferase, GenBank Y14814-derived protein GI 2440135, L-Selenocysteine-tRNASec synthase selenocysteine synthase, L-Selenocysteine-tRNASel synthase, More, Sec synthase, SecS, SelA, selA gene product, Selenocysteine synthase, Selenocysteine synthase (Moorella thermoacetica strain DSM521 clone pCTA 100/pCTAB1 gene selA), Selenocysteine-tRNA synthase, Selenocysteinyl-tRNA synthase, Selenocysteinyl-tRNA(Sec) synthase, SLA, soluble liver antigen, Synthase, selenocysteine (Moorella thermoacetica clone pCTA100/pCTAB1 gene selA), Synthase, selenocysteinyl-transfer ribonucleate
EC Number 2.9.1.1
CAS Registry Number 183869-06-9;211752-49-7
Comments A pyridoxal 5′-phosphate enzyme identified in?Escherichia coli. Recognises specifically tRNASec-species. Binding of tRNASec?also occurs in the absence of the seryl group. 2-Aminoacryloyl-tRNA, bound to the enzyme as an imine with the pyridoxal phosphate, is an intermediate in the reaction. Since the selenium atom replaces oxygen in serine, the product may also be referred to as?L-selenoseryl-tRNASec. The symbol Sel has also been used for selenocysteine but Sec is preferred.
Cofactor pyridoxal 5′-phosphate
History
Reactions L-seryl-tRNA(Sec) + selenophosphate = L-selenocysteinyl-tRNA(Sec) + phosphate.

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