tRNA (N6-L-threonylcarbamoyladenosine37-C2)-methylthiotransferase EC#: 2.8.4.5

Product Name tRNA (N6-L-threonylcarbamoyladenosine37-C2)-methylthiotransferase
Example Structure Example Structure of tRNA (N6-L-threonylcarbamoyladenosine37-C2)-methylthiotransferase EC#: 2.8.4.5
Synonyms CDKAL1, methylthio-threonylcarbamoyl-adenosine transferase B, MtaB, YqeV
EC Number 2.8.4.5
CAS Registry Number
Comments The enzyme, which is a member of the?S-adenosyl-L-methionine-dependent radical (radical AdoMet) enzymes superfamily, binds two [4Fe-4S] clusters as well as the transferred sulfur. The sulfur donor is believed to be one of the [4Fe-4S] clusters, which is sacrificed in the process, so that?in vitro?the reaction is a single turnover. The identity of the electron donor is not known.
Cofactor iron-sulfur
History
Reactions N(6)-L-threonylcarbamoyladenine(37) in tRNA + sulfur-(sulfur carrier) + 2 S-adenosyl-L-methionine + reduced electron acceptor = 2-methylthio- N(6)-L-threonylcarbamoyladenine(37) in tRNA + S-adenosyl-L-homocysteine + (sulfur carrier) + L-methionine + 5′-deoxyadenosine + electron acceptor.

Buy Reagent

No reagent supplier? Send quick inquiry to ChemWhat
Want to be listed here as a reagent supplier? (Paid service) Click here to contact ChemWhat

Approved Manufacturers

Want to be listed as an approved manufacturer (Free service but requires approvement)? Please download and fill out this form and send back to [email protected]

More Suppliers

Watson International Limited Send quick inquiry to Watson
Want to be listed here as a supplier? (Paid service) Click here to contact ChemWhat

Contact Us for Other Help

Contact us for other services like technology transfer, synthetic literature, sourcing, advertisement, etc. Click here to contact ChemWhat