Anti-Serum Amyloid A (SAA) Antibody

AntigenDescriptionProperties
Safety InformationImagesOther Info

Antigen

NameSerum Amyloid A (SAA)
SynonymsSAA; PIG4; SAA2; TP53I4

Description

NameAnti-Serum Amyloid A (SAA) Antibody
SynonymsAnti-SAA1; Serum Amyloid A Antibody IHC-plus; Serum amyloid A protein; Serum Amyloid A; Serum amyloid A-1 protein; SAA; Serum amyloid A1; PIG4; Human SAA1; SAA; Serum Amyloid A
HostMouse; Goat; Rabbit
ReactivityAll species
Antibody Product Type  Primary
UseDetection; Capture
Conjugate Unconjugated; Biotin; APC; Alkaline Phosphatase (AP); FITC; HRP; PE
SpecifityRecognizes natural and recombinant human SAA. Does not show any cross-reactivity with other human cytokines or growth factors tested such as IL-1b, IL-8, MCAF, TGF-b and EGF.
ApplicationELISA; Immunohistochemistry (IHC); Western Blotting (WB); Immunofluorescence (fixed cells) (IF/ICC); Immunoprecipitation (IP); Cell-ELISA (cELISA); Immunoassay (IA); Immunocytochemistry (ICC)

Properties

FormLiquid/Lyophilized
HandlingThe antibody solution should be gently mixed before use.
Storage ConditionStore at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for a year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
ClonalityMonoclonal/Polyclonal
IsotypeIgG

Safety Information

RIDADRNONH for all modes of transport
Flash Point(F) Not applicable
Flash Point(C) Not applicable

Images

Anti-Serum Amyloid A Antibody WBAnti-Serum Amyloid A (SAA) Antibody WB
Turbidimetric Fit CurveSAA turbidimetric fit curve
Anti-Serum Amyloid A Antibody IHCAnti-Serum Amyloid A (SAA) Antibody IHC

Other Info

About the antigenSerum amyloid A proteins are a family of apolipoproteins associated with high-density lipoprotein (HDL) in plasma. Different isoforms are expressed constitutively at different levels or in response to inflammatory stimuli. The serum amyloid A family comprises a number of differentially expressed apolipoproteins, acute-phase SAA1 and SAA2, the former being the major component in plasma and constitutive SAAs. Although the liver is the primary site of synthesis of both SAA types extrahepatic production has been reported. The in vivo concentrations increase by as much as 1000 fold during inflammation. Several studies have expressed its importance in the diagnosis and monitoring of various diseases. Pathological SAA values are often detected in association with normal CRP concentrations; It rises earlier and more sharply than CRP. Recently, a broader view of SAA expression and function has been emerging.

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